Mch3, a novel apoptotic protease, nucleic acids encoding and methods of use

   
   

The invention provides an isolated gene encoding Mch3, or functional fragment thereof. Also provided is an isolated nucleic acid sequence encoding Mch3 or functional fragment thereof. The gene or nucleic acid sequence can be single or double stranded nucleic acids corresponding to coding or non-coding strands of the Mch3 nucleotide sequence. An isolated Mch3 polypeptide or functional fragment thereof is also provided.

L'invention fournit un gène d'isolement codant Mch3, ou le fragment fonctionnel en. En outre fourni est un ordre d'isolement d'acide nucléique codant Mch3 ou fragment fonctionnel en. L'ordre de gène ou d'acide nucléique peut être les acides nucléiques échoués simples ou doubles correspondant aux rives de codage ou de non-codage de l'ordre du nucléotide Mch3. Un polypeptide Mch3 d'isolement ou un fragment fonctionnel en est également fourni.

 
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< Antibody that specifically binds an Mch5 polypeptide

< Inhibitors of the ICE/ced-3 family of cysteine proteases

> Antibody that specifically binds an Mch4 polypeptide

> Treatment of inflammation-associated disorders using interleukin-1.beta.-converting enzyme (ICE)/CED-3 family inhibitors

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