Compounds having activity as inhibitors of cytochrome P450RAI
   
   

Compounds having Formula 4 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids. ##STR1##

Combina ter a fórmula 4 wherein os símbolos têm o meaning definido na especificação são inibidores do enzyme do cytochrome P450RAI (inducible ácido retinoic), e são usados para as doenças de tratamento responsivas ao tratamento por retinoids. ## do ## STR1
 
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> (1,2,3,4-tetrahydroquinolin-8-yl)-heptatrienoic acid derivatives having serum glucose reducing activity

> Quinoline-4-carboxamide derivatives as NK-3 and NK-2 receptor antagonists
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