Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins

   
   

Methods of detecting and treating rapidly growing exogenous cells, such as Protista, or parasites, that preferentially accumulate a photoactivatable porphyrin in which 5-aminolevulinic acid or precursor thereof is administered to the patient, or contacted to the exogenous cells, in an amount sufficient to induce synthesis fluorescence and/or photosensitizing concentrations of a protoporphyrin IX in the exogenous cells, followed by exposure of the exogenous cells to light of photoactivating wavelengths.

Os métodos de detectar e de tratar pilhas exogenous ràpidamente crescentes, tais como Protista, ou os parasites, que acumulam preferentially um porphyrin photoactivatable em que o ácido 5-aminolevulinic ou o precursor disso são administrados ao paciente, ou contatados às pilhas exogenous, em uma quantidade suficiente induzir o fluorescence da síntese e/ou concentrações photosensitizing de um protoporphyrin IX nas pilhas exogenous, seguiram pela exposição das pilhas exogenous à luz de wavelengths photoactivating.

 
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