Stent treatment apparatus and method

   
   

Manual stent manipulation before implantation results in foreign body contamination and increased neointimal hyperplasia. Rinsing commercially available sterile stents with high pressure immediately before implantation eliminates residual surface stent contaminants and reduces inflammation elicited by stent struts. Ex-vivo stent expansion and surface analysis revealed that rinsed stents had fewer surface contaminants than untouched or handled stents. In a porcine stent restenosis model, rinsed stents elicited less inflammation and less neointimal hyperplasia at one month than handled and untouched stents. Pressure-rinsing of coronary stents immediately before implantation reduces inflammation and neointimal hyperplasia.

De hand stent manipulatie vóór inplanting resulteert in buitenlandse lichaamsverontreiniging en verhoogde neointimal hyperplasia. Het spoelen van commercieel beschikbare steriele stents met hoge druk onmiddellijk vóór inplanting elimineert overblijvende oppervlakte stent verontreinigende stoffen en vermindert ontsteking die door stent stutten wordt onthuld. Openbaarden de stent uitbreiding ex-vivo en de oppervlakteanalyse dat gespoeld stents minder dan onaangeroerd of behandelde oppervlakteverontreinigende stoffen stents had. In een varkens stent gespoeld restenosismodel, stents onthuld minder ontsteking en minder neointimal hyperplasia bij één maand dan behandelde en onaangeroerde stents. Druk-spoelt van coronaire stents onmiddellijk vóór inplanting vermindert ontsteking en neointimal hyperplasia.

 
Web www.patentalert.com

< Communicative glove containing embedded microchip

< Compositions comprising hydrogenated block copolymers and end-use applications thereof

> Supported group 8-10 transition metal olefin polymerization catalysts

> Method of making interpolymers and products made therefrom

~ 00105