Compositions and methods for the therapy and diagnosis of cancer,
particularly ovarian cancer, are disclosed. Illustrative compositions
comprise one or more ovarian tumor polypeptides, immunogenic portions
thereof, polynucleotides that encode such polypeptides, antigen presenting
cell that expresses such polypeptides, and T cells that are specific for
cells expressing such polypeptides. The disclosed compositions are useful,
for example, in the diagnosis, prevention and/or treatment of diseases,
particularly ovarian cancer.
