Expression and refolding of truncated recombinant major outer membrane protein antigen (R56) of orientia tsutsugamushi and its use in antibody based detection assays and vaccines

   
   

A recombinant, refolded non-fusion polypeptide expressed from a truncated r56 gene of the causative agent of scrub typhus, Orientia tsutsugamushi. The invention is useful for detecting prior exposure to scrub typhus and as a component in vaccine formulations.

Un de recombinaison, refolded le polypeptide de non-fusion exprimé d'un gène r56 tronqué de l'agent causatif de frotte le typhus, tsutsugamushi d'Orientia. L'invention est utile pour détecter l'exposition antérieure pour frotter le typhus et comme composant dans des formulations vacciniques.

 
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