Cyclic peptides as potent and selective melanocortin-4 receptor antagonists

   
   

Cyclic peptides of formula I are potent and selective antagonists of melanocortin-4 receptors, and as such are useful research tool for the determination of the physiological roles of the MC-4 receptor, as well as for the diagnosis, treatment or prevention of disorders or diseases mediated through the MC-4 receptor.

I peptidi ciclici della formula I sono antagonisti potenti e selettivi dei ricevitori melanocortin-4 e poichè tali sono attrezzo utile di ricerca per la determinazione dei ruoli fisiologici del ricevitore MC-4, così come per la diagnosi, il trattamento o la prevenzione dei disordini o delle malattie mediati tramite il ricevitore MC-4.

 
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