Nucleic acid molecules encoding DRT111 and uses thereof

   
   

Novel DRT111 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to an isolated, full-length DRT111 protein, the invention further provides isolated DRT111 fusion proteins, antigenic peptides and anti-DRT111 antibodies. The invention also provides DRT111 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a DRT111 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.

Os polypeptides da novela DRT111, as proteínas, e as moléculas do ácido nucleic são divulgados. Além a uma proteína DRT111 isolada, full-length, a invenção fornece mais mais proteínas isoladas da fusão DRT111, peptides antigenic e antibodies anti-DRT111. A invenção fornece também moléculas do ácido DRT111 nucleic, vetores recombinant da expressão que contêm uma molécula do ácido nucleic da invenção, as pilhas de anfitrião em que os vetores da expressão foi introduzido e os animais transgenic non-human em que um gene DRT111 foi introduzido ou disrupted. O diagnostic, a seleção e os métodos therapeutic utilizando composições da invenção são fornecidos também.

 
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