The present invention provides novel immunosuppressive agents. In particular, the invention provides immunosuppressive agents that bind calcineurin and/or that inhibit interaction between calcineurin and NF-AT. The invention also provides analogs of these agents, nucleic acids encoding the agents and/or their analogs, gene therapy vectors, etc., and methods of making and using them.

La présente invention fournit les agents immunosuppressifs de roman. En particulier, l'invention fournit les agents immunosuppressifs qui lient le calcineurin et/ou qui empêchent l'interaction entre le calcineurin et le NF-AT. L'invention fournit également des analogues de de ces agents, acides nucléiques codant les agents et/ou leurs analogues, vecteurs de thérapie de gène, etc., et méthodes de la fabrication et les employer.

 
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