Dictyostatin-1 has been found to stabilize microtubules and prohibit their depolymerization to free tubulin. Because of these activities, the dictyostatin compounds can be used in the treatment of a number of diseases in which aberrant cellular proliferation occurs such as drug-sensitive and drug-resistant cancers, autoimmune disorders, and inflammatory diseases.

 
Web www.patentalert.com

< Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use

< Transgenic mice over-expressing receptor for advanced glycation endproduct (RAGE) and mutant APP in brain and uses thereof

> Apparatus and method for imaging objects with wavefields

> Thermoplastic polymers with dispersed fluorocarbon additives
~ 00097