Novel polypeptides involved in the biosynthesis of cobalamines and/or cobamides, in particular coenzyme B.sub.12, genetic material responsible for expressing these polypeptides, and a method for preparing them, are described. A method for amplifying the production of cobalamines, and particularly coenzyme B.sub.12, using recombinant DNA techniques, are also described.

Описаны полипептиды романа, котор включили в биосинтез cobalamines and/or cobamides, в частности кофермента B.sub.12, генетического материала ответственного для выражать эти полипептиды, и метода для подготовлять их. Метод для усиливать продукцию cobalamines, и определенно кофермент B.sub.12, использующ рекомбинатные методы ДНАА, также описаны.

 
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