Modified oligonucleotides containing at least one 2',5'-internucleotide linkage are provided. The oligonucleotides of the invention may also bear additional substituents at the 2'- and 3'-positions.

I oligonucleotides modificati che contengono almeno un 2', il collegamento 5'-internucleotide sono forniti. I oligonucleotides dell'invenzione possono anche sopportare i sostituenti supplementari al 2'- ed a 3'-positions.
 
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