Indolylmaleimide derivatives comprising either a substituted phenyl, naphthyl, tetrahydronaphthyl, quinazolinyl, quinolyl, isoquinolyl or pyrimidinyl residue have interesting pharmaceutical properties, e.g. in the treatment and/or prevention of T-cell mediated acute or chronic inflammatory diseases or disorders, autoimmune diseases, graft rejection or cancer.

Los derivados de Indolylmaleimide que abarcan un residuo substituido del fenilo, de la naftílico, del tetrahydronaphthyl, del quinazolinyl, del quinolyl, del isoquinolyl o del pyrimidinyl tienen características farmacéuticas interesantes, e.g. en el tratamiento y/o la prevención de enfermedades mediadas T-ce'lula o de desórdenes inflamatorios agudos o crónicos, de enfermedades autoinmunes, del rechazamiento del injerto o del cáncer.

 
Web www.patentalert.com

< Method for searching physiologically active substances, process for producing these substances and drugs found by the searching method

< Benzimidazole vascular damaging agents

> Therapeutically active and selective heterocyclic compounds that are inhibitors of the enzyme DPP-IV

> Benzopyrancarboxylic acid derivatives for the treatment of diabetes and lipid disorders

~ 00090