The method for the holding in flotation of a substance such as a tissue
part in a bioreactor (61) is characterized in that the substance (73) is
acted upon with a fluid; and in that the flow of the fluid acts counter to
gravity in such a manner that the substance (73) is held in flotation. The
bioreactor (61) with a container (62) for a substance (73) which is to be
acted upon with fluid comprises a first flow chamber (66a) to which a
flowing fluid can be supplied, with the first flow chamber (66a) being
designed in such a manner that the fluid which flows upwardly therein has
a lower speed with increasing height.