Compounds, compositions and methods are provided for modulating the expression of PTP1B. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PTP1B. Methods of using these compounds for modulation of PTP1B expression and for treatment of diseases associated with expression of PTP1B are provided.

Смеси, составы и методы обеспечены для модуляции выражения PTP1B. Составы состоят из смесей antisense, определенно пристрелнных олигонуклеотидов antisense, к нуклеиновым кислотам шифруя PTP1B. Обеспечены методы использования этих смесей для модуляции выражения PTP1B и для обработки заболеваний связанных с выражением PTP1B.

 
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