A method for training of auditory and graphical discrimination in humans, and a human's short term memory, is provided within an animated game environment. The method provides a number of stimulus sets, each stimulus set having similar sounding phonemes associated with graphemes. Upon initiation of a trial, a grid of tiles is presented to a subject. The subject selects the tiles, one at a time. As the tiles are selected, an associated phoneme is presented to the subject. The subject clears away tiles by pairing them with identical tiles. When all the tiles in a trial are cleared, the subject is either promoted or demoted in skill level. Promotion/demotion varies the number of tiles presented, the phonemes used within each trial, and the amount of audio processing that is applied to the phonemes.