Disclosed is a method for pre-design estimation of coupling noise and avoidance of coupling noise failures in interconnects. An initial routing of a plurality of nets is estimated utilizing global paths. Then, the worst-case and average-case models for various parameters of each net are evaluated. With these models, a noise analysis is completed by which a determination is made whether coupling noise of any one of the nets is above a threshold level for noise-induced failure (i.e., a noise-failure threshold). When it is determined that the estimated coupling noise of a net falls below the noise-failure threshold, a response mechanism is triggered for later implementation during detailed routing of the nets to prevent the coupling noise from reaching the noise-failure threshold.