A purified, soluble lymphocyte-derived antimicrobial protein that has a molecular weight of 16 kD on SDS-PAGE, is inactivated by heating at 56.degree. C. for 30 minutes or by treatment with trypsin, is expressed by CD3-, CD2+ cytokine-stimulated cells', and is active against Gram positive or Gram-negative bacteria including Staphylococcus aureus.

Una proteina antimicrobica linfocita-derivata purificata e solubile che ha un peso molecolare di kD 16 su SDS-PAGE, è inattivata riscaldando a 56.degree. Il C. per 30 minuti o dal trattamento con tripsina, è espresso da CD3 -, cellule cytokine-stimolate CD2+ ed è attivo contro i batteri gram-positivi o gram-negativi compreso lo stafilococco aureo.

 
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