A method of producing pharmaceutical compositions using O-desmethyl-N-mono-desmethyl-tramadol for the treatment of pain and various related indications, pharmaceutical compositions containing O-desmethyl-N-mono-desmethyl-tramadol, and a method of treating pain, urinary incontinence, diarrhea or pruritus using O-desmethyl-N-mono-desmethyl-tramadol.

Um método de produzir usar-se pharmaceutical das composições O-desmethyl-N-o-desmethyl-N-mono-desmethyl-tramadol-desmethyl-tramadol para o tratamento da dor e várias indicações relacionadas, conter pharmaceutical das composições O-desmethyl-N-o-desmethyl-N-mono-desmethyl-tramadol-desmethyl-tramadol, e um método de tratar a dor, usar-se urinary do incontinence, do diarrhea ou do pruritus O-desmethyl-N-o-desmethyl-N-mono-desmethyl-tramadol-desmethyl-tramadol.