The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.

A invenção atual é dirigida aos polypeptides da novela que têm a identidade da seqüência com IL-17, receptors IL-17 e às moléculas do ácido nucleic que codificam aqueles polypeptides. São fornecidos também nisto os vetores e as pilhas de anfitrião que compreendem aquelas seqüências do ácido nucleic, moléculas chimeric do polypeptide que compreendem os polypeptides da invenção atual fundida às seqüências heterologous do polypeptide, os antibodies que ligam aos polypeptides da invenção atual e aos métodos para produzir os polypeptides da invenção atual. São fornecidos mais mais nisto os métodos para tratar disorders cartilaginous degenerative e outras doenças inflammatory.

 
Web www.patentalert.com

< Aesthetic dental materials

< Flat-type display

> Patterned deposition of antibody binding protein for optical diffraction-based biosensors

> Liquid transport member for high flux rates between a port region and an opening

~ 00075