Compounds that inhibit 5-alpha-reductase are provided. The compounds are used to treat prostate cancer, breast cancer, obesity, skin disorders and baldness.

Des composés qui empêchent 5-alpha-reductase sont fournis. Les composés sont employés pour traiter le cancer de prostate, le cancer de sein, l'obésité, les désordres de peau et la calvitie.
 
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> Subtilisin protease variants having amino acid deletions and substitutions in defined epitope regions

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