Two FADD-like anti-apoptotic proteins that regulate Fas/TNFR1- or UV-induced apoptosis are disclosed. Nucleotide sequences encoding the proteins are disclosed as are methods of using the nucleic acid molecules and making the proteins. Pharmaceutical compositions and methods of using the same are disclosed. Reagents, kits and methods of identifying compounds that inhibit anti-apoptotic activity of the proteins and methods of identifying compounds that inhibit binding activity of the proteins are disclosed.

Dos FADD-como las proteínas anti-apoptotic que regulan el apoptosis de Fas/TNFR1- o UV-inducido se divulgan. Las secuencias del nucleotide que codifican las proteínas se divulgan al igual que métodos de usar las moléculas del ácido nucleic y de hacer las proteínas. Las composiciones y los métodos farmacéuticos de usar igual se divulgan. Los reactivo, los kits y los métodos de identificar los compuestos que inhiben la actividad anti-apoptotic de las proteínas y de los métodos de identificar los compuestos que inhiben la actividad obligatoria de las proteínas se divulgan.

 
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> Polynucleotides encoding flavivirus and alphavirus multivalent antigenic polypeptides

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