Binding of a molecule to a molecular receptor is sensed using a transistor having a gate located at a binding site. The channel conductance of the transistor is modified by a charge associated with the molecule when the molecule binds with the molecular receptor. A modified electrical characteristic of the transistor which results is sensed to sense the binding event. Electric field enhancement is provided by applying a voltage to the gate. A second sensing transistor can be coupled to the sensing transistor to form a differential pair. The differential pair allows for enhancing and sensing of differential binding events.

 
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< Photoelectric synthesis of DNA or protein probe arrays

< Electric field amplified oligonucleotide ligase analysis

> Method and system for performing a binding assay

> Sensors for electrically sensing binding events for supported molecular receptors

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