The present invention relates to the compounds of formula: ##STR1## in which R.sub.1, R.sub.2, R.sub.3, E, A, X, Z, p and n are as defined herein. These compounds are aldose reductase inhibitors.

La presente invenzione riguarda i residui della formula: ## del ## STR1 in quali R.sub.1, R.sub.2, R.sub.3, E, A, X, Z, p e n รจ come definita qui. Questi residui sono inibitori della riduttasi dell'aldoso.

 
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