There are provided N-acetyl-D-glucosamine deacetylase capable of hydrolyzing acetamide group of N-acetyl-D-glucosamine to produce D-glucosamine and acetic acid, which has the following physicochemical properties: (1) Substrate specificity: N-acetyl-D-glucosamine monomer, not the oligomer or polymer thereof; (2) Optimal pH: 7.8-8.2 at 37.degree. C.; (3) Stable pH: 6.0-9.0 at 45.degree. C.; (4) Optimal temperature: 28.degree.-39.degree. C.; (5) Molecular weight: 70,000-200,000 as determined using TSK-gel G-3000 SW column, and a process for preparing the same using a microorganism belonging to Vibrio sp.

Há deacetylase fornecido do N-acetyl-D-n-acetyl-D-glucosamine capaz de hydrolyzing o grupo da acetamida do N-acetyl-D-n-acetyl-D-glucosamine para produzir o d-glucosamine e o ácido acetic, que tem as seguintes propriedades physicochemical: (1) specificity da carcaça: monomer do N-acetyl-D-n-acetyl-D-glucosamine, não o oligomer ou o polímero disso; (2) pH optimal: 7.8-8.2 em 37.degree. C.; (3) pH estável: 6.0-9.0 em 45.degree. C.; (4) temperatura optimal: 28.degree.-39.degree. C.; (5) peso molecular: 70.000-200.000 como coluna usando-se determinada do interruptor do TSK-tSK-gel G-3000, e um processo para preparar o mesmo que usa um microorganism que pertence ao sp do vibrio.

 
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> Histone deacetylase as target for antiprotozoal agents

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