A compound of the formula I: ##STR1## wherein A and C are independently H, alkyl of 1-6 carbon atoms, hydroxy, or alkoxy of 1-6 carbon atoms; B is hydroxy, alkoxy of 1-6 carbon atoms --CO.sub.2 Z, --O(CH.sub.2).sub.m CO.sub.2 Z, --SO.sub.3 Z, --OPO.sub.3 Z.sub.2 ; and Y is cyano, ##STR2## --C(NR.sub.1 R.sub.2).dbd.C(CN).sub.2 ; wherein X.dbd.O or S, and R.sub.1 and R.sub.2 are independently H, benzyl, --CH(CH.sub.3)C.sub.6 H.sub.6, --(CH.sub.2).sub.n C.sub.6 H.sub.6, phenyl; --CO.sub.2 R; n=2-4; R is lower alkyl of 1-6 carbon atoms; m=1-4 and Z is H, a cation or lower alkyl of 1-6 cabon atoms; is used for treating inflammation, immunological diseases or diabetes.

Een samenstelling van formule I: ## STR1 ## waarin A en C onafhankelijk H, alkyl van 1-6 koolstofatomen zijn, hydroxy, of alkoxy van 1-6 koolstofatomen; B is hydroxy, alkoxy van 1-6 koolstofatomen -- CO.sub.2 Z, -- O(CH.sub.2).sub.m CO.sub.2 Z, -- SO.sub.3 Z, -- OPO.sub.3 Z.sub.2; en Y is cyano, ## STR2 ## -- C(NR.sub.1 R.sub.2).dbd.C(CN).sub.2; waarin X.dbd.O of S, en R.sub.1 en R.sub.2 onafhankelijk H zijn, benzyl, -- CH(CH.sub.3)C.sub.6 H.sub.6, -- phenyl (CH.sub.2).sub.n C.sub.6 H.sub.6; -- CO.sub.2 R; n=2-4; R is lagere alkyl van 1-6 koolstofatomen; m=1-4 en Z is H, een kation of lagere alkyl van 1-6 cabonatomen; wordt gebruikt voor het behandelen van ontsteking, immunologische ziekten of diabetes.

 
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