The subject invention provides novel compounds and compositions for the safe and effective treatment of gastroesophageal reflux and related conditions. In a preferred embodiment, the compositions of the subject invention comprise esterified cisapride derivatives. These compositions possess potent activity in treating gastroesophageal reflux disease and substantially reduce adverse effects associated with the administration of cisapride. These adverse effects include, but are not limited to, diarrhea, abdominal cramping and elevations of blood pressure and heart rate.

L'invention soumise fournit des composés et des compositions de roman pour le traitement sûr et efficace du reflux gastroesophageal et des conditions relatives. Dans un mode de réalisation préféré, les compositions de l'invention soumise comportent les dérivés estérifiés de cisapride. Ces compositions possèdent l'activité efficace dans la maladie gastroesophageal de traitement de reflux et réduisent sensiblement des effets nuisibles liés à l'administration du cisapride. Ces effets nuisibles incluent, mais ne sont pas limités à, diarrhée, restriction abdominale et altitudes de tension artérielle et de fréquence cardiaque.

 
Web www.patentalert.com

< Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system

< Antibodies specific for semaphorin-like polypeptides

> 2,1-oxazoline and 1,2-pyrazoline-based inhibitors of dipeptidyl peptidase IV and method

> Method and compositions for treatment of the aging eye

~ 00068