Disclosed is a method of stimulating adult corneal endothelial cell proliferation, which includes incubation of corneal endothelium to a mitogen-containing medium and then to an agent that interrupts cell-cell contacts in the adult corneal endothelial cells, and subsequently, as needed, further incubation in the mitogen-containing medium. The cell-cell contact-interrupting agent is preferably a calcium chelator.

Se divulga un método de estimular la proliferación endothelial córnea de la célula del adulto, que incluye la incubación del endotelio córneo a un medio mitogen-que contiene y entonces a un agente que interrumpa contactos de la ce'lula-ce'lula en las células endothelial córneas del adulto, y posteriormente, como incubación necesitada, posterior en el medio mitogen-que contiene. El agente de entrar en contacto con-interrupcio'n de la ce'lula-ce'lula es preferiblemente un chelator del calcio.

 
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