The present invention relates to polyspecific binding molecules and particularly single-chain polyspecific binding molecules that include at least one single-chain T-cell receptor (sc-TCR) covalently linked through a peptide linker sequence to at least one single-chain antibody (sc-Ab). Further disclosed are methods and compositions for testing and using the molecules.

La actual invención se relaciona con las moléculas obligatorias polyspecific y particularmente las moléculas obligatorias polyspecific single-chain que incluyen por lo menos un receptor single-chain de la T-ce'lula (sc-TCR) covalente ligado con una secuencia del linker del peptide por lo menos a un anticuerpo single-chain (tapajunta). Más futuros divulgados son métodos y composiciones para probar y usar las moléculas.

 
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