Novel pyrrolo[3,2-d]pyrimidine derivatives of the following general formula ##STR1## are disclosed. These compounds are useful in the treatment of bacterial infections such as Toxoplasmosis gondii and Pneumocystis carinii, and various types of cancer, through their action on dihydrofolate reductase and thymidylate syndmase enzymes. Methods of inhibiting these enzymes, by administration of these compounds, are also disclosed.

I derivati del romanzo pyrrolo[3,2-d]pyrimidine di seguente ## generale del ## STR1 di formula sono rilevati. Questi residui sono utili nel trattamento delle infezioni batteriche quali il gondii di toxoplasmosi ed il carinii di Pneumocystis e nei vari tipi di cancri, con la loro azione sugli enzimi di syndmase della riduttasi e del thymidylate del dihydrofolate. I metodi di inibizione dei questi enzimi, tramite la gestione di questi residui, inoltre sono rilevati.

 
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