The invention concerns new tumor necrosis factor receptor associated factors, designated TRAF. The new factors are capable of specific association with the intracellular domain of the type 2 TNF receptor (TNF-R2), and are involved in the mediation of TNF biological activities.

A invenção concerne os fatores associados do fator do necrosis do tumor receptor novo, designados TRAF. Os fatores novos são capazes da associação específica com o domínio intracellular do tipo 2 receptor de TNF (TNF-R2), e são envolvidos no mediation de atividades biológicas de TNF.
 
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