The invention pertains to a nucleic acid transfer system including a
translocation domain of toxins, especially of diphtheria toxin suitable
for targeting a nucleic acid, e.g. a gene, to a specific cell, and
obtaining expression of said nucleic acid. The nucleic acid transfer
system of the invention comprises a multidomain protein component and a
nucleic acid component. Furthermore, the present invention relates to the
multidomain protein, a nucleic acid encoding said protein, suitable
amplification and expression systems for said nucleic acid, and processes
for the preparation and uses of the above subject matters.