Transgenic non-mammalian animals, e.g. flies, that exhibit an adult onset neurodegenerative phenotype, as well as methods for preparing the same, are provided. Also provided are methods of using the subject transgenic non-mammalian animals to identify compounds having activity with respect to adult onset neurodegenerative diseases. Finally, kits for screening compounds for anti-neurodegenerative activity are provided.

Обеспечивают животных Transgenic нон-non-mammalian, например мухы, которые exhibit фенотип onset взрослого neurodegenerative, также,как методы для подготовлять эти же. Также обеспечены методы использования subject transgenic нон-non-mammalian животных определить смеси имея деятельность по отношению к заболеваниям onset взрослого neurodegenerative. Окончательно, обеспечены наборы для смесей скрининга для anti-neurodegenerative деятельности.

 
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