The invention relates to use of substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atherosclerosis and other coronary artery diseases. Preferred tertiary-heteroalkylamine compounds are substituted N,N-disubstituted cycloalkyl aminoalcohols. A preferred specific N,N-disubstituted cycloalkyl aminoalcohol is the compound: ##STR1##

De uitvinding heeft op gebruik van gesubstitueerde polycyclic aryl en heteroaryl nuttige betrekking tertiair-heteroalkylaminesamenstellingen aangezien de inhibitors van cholesteryl ester proteïne (CETP; overdracht eiwit-i van het plasmalipide) en samenstellingen, samenstellingen en methodes overbrengen om atherosclerose en andere kransslagaderziekten te behandelen. De aangewezen tertiair-heteroalkylaminesamenstellingen zijn gesubstitueerd N, n-Disubstituted cycloalkylaminoalcohols. Aangewezen specifiek N, n-Disubstituted cycloalkylaminoalcohol is de samenstelling: ## STR1 ##

 
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