2-lithio-5-halopyridine is formed as a predominant component of a reaction mixture by reacting BuLi with 2,5-dihalopyridine in a non-coordinating solvent.

2-lithio-5-halopyridine es formado como componente predominante de una mezcla de reacción reaccionando BuLi con 2,5-dihalopyridine en un solvente no-que coordina.