The present invention regards personal rescue devices for use by individuals separated from watercraft in open water. Provided are an inflation valve and rescue device having high reliability and insensitivity to environmental conditions. The inflation valve includes a fusible element, such as a stainless steel wire, which is fused or broken by application of an electrical current. Prior to use, the fusible element retains a trigger in a position to prevent a penetrator from releasing compressed gas from a gas canister. Upon activation and breaking of the fusible element, the penetrator is forced into the gas canister releasing gas to inflate the rescue device. The rescue device is retained within a deployment canister having a cover that is easily sealed and resealed to ease maintenance and operation. The rescue device is incorporated into a remotely activated rescue system including a miniature radio frequency transmitter which may be worn on a user's body such as on a wrist strap. In the remote system, a receiver and power supply for deploying the rescue device is retained on a watercraft. Various other embodiments incorporate the electrically activated inflation valve with other rescue devices and in conjunction with water activated valves.