3-[N'-(benzoyl)thioureido]-5-substituted-1,2,4-thiadiazoles are debenzoylated in an aqueous KOH solution. This process provides the 5-substituted-3-thioureido-1,2,4-thiadiazoles in unexpectedly high yield and purity as compared to similar processes employing NaOH.

3-[N'-(benzoyl)thioureido]-5-substituted-1,2,4-thiadiazoles são debenzoylated em uma solução aqueous do KOH. Este processo fornece o 5-substituted-3-thioureido-1,2,4-thiadiazoles no rendimento e no purity inesperada elevados em comparação aos processos similares que empregam o NaOH.