A compound of formula (I) wherein m, n, o, p, q, r, A, B, D, E, R.sup.1, R.sup.2,R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7 and R.sup.8 are as defined in the description, useful in the treatment of respiratory, allergic, rheumatoid, body weight regulation, inflammatory and central nervous system disorders such as asthma, chronic obstructive pulmonary disease, adult respiratory diseases syndrome, shock, fibrosis, pulmonary hypersensitivity, allergic rhinitis, atopic dermatitis, psoriasis, weight control, rheumatoid arthritis, cachexia, crohn's disease, ulcerative colitis, arthritic conditions and other inflammatory diseases, depression, multi-infarct dementia and AIDS.

Un residuo della formula (i) in cui la m., il N, la o, la p, la q, le r, A, la B, la D, la E, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7 e R.sup.8 sono come definiti nella descrizione, utile nel trattamento dei disordini di regolazione del peso corporeo respiratorio, allergico, rheumatoid, del sistema nervoso infiammatorio e centrale quale asma, della malattia polmonare ostruttiva cronica, della sindrome respiratoria di malattie dell'adulto, della scossa, della fibrosi, dell'ipersensibilità polmonare, del rhinitis allergico, della dermatite atopica, dello psoriasis, del controllo del peso, dell'artrite rheumatoid, della cachessia, della malattia dei crohn, del colitis ulcerative, delle circostanze arthritic e di altre malattie infiammatorie, la depressione, of formula (I) wherein m, n, o, p, q, r, A, B, D, E, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7 and R.sup.8 are as defined in the description, useful in the treatment of respiratory, allergic, rheumatoid, body weight regulation, inflammatory and central nervous system disorders such as asthma, chronic obstructive pulmonary disease, adult respiratory diseases syndrome, shock, fibrosis, pulmonary hypersensitivity, allergic rhinitis, atopic dermatitis, psoriasis, weight control, rheumatoid arthritis, cachexia, crohn's disease, ulcerative colitis, arthritic conditions and other inflammatory diseases, depression, multi-infarct demenza ed AIDS.

 
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