Compounds having Formula 8 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids. ##STR1##

Compone tener fórmula 8 en donde los símbolos tienen el significado definido en la especificación son inhibidores de la enzima del cytochrome P450RAI (inducible ácido retinoic), y son utilizados para las enfermedades que tratan responsivas al tratamiento por los retinoids. ## del ## STR1

 
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