The present invention relates to a method of identifying compounds which act as inverse agonists of the 5-HT2A receptor, the method comprising contacting a constitutively active 5-HT2A receptor with at least one test compound and determining any decrease in the level of basal activity of the receptor so as to identify a test compound which is an inverse agonist of the 5-HT2A receptor. Such inverse agonists may be used in the treatment of schizophrenia and related psychoses.

 
Web www.patentalert.com

< (none)

< Positively charged non-natural amino acids, methods of making thereof, and use thereof in peptides

> 18-substituted-19-nor-vitamin D compounds

> (none)

~ 00030