Phenidate drug formulations are provided having reduced potential for drug abuse. Dosage forms for treating Attention Deficit Disorder, Attention Deficit Hyperactivity Disorder, AIDS Dementia Complex and cognitive decline in HIV-AIDS are provided which minimize drug hypersensitivity, toxicity, side effects, euphoric effect, and drug abuse potential. Such dosage forms comprise D-threo stereoisomer of a phenidate in the substantial absence of all other stereoisomers.

Os formulations da droga de Phenidate são fornecidos reduzindo o potencial para o abuso da droga. Os formulários de dosage para o disorder de deficit de atenção de tratamento, o disorder do hyperactivity do deficit da atenção, do dementia do AIDS declínio complexo e cognitive em HIV-AIDS são fornecidos que minimizam o hypersensitivity da droga, o toxicity, efeitos laterais, o efeito euphoric, e o potencial do abuso da droga. Tais formulários de dosage compreendem o stereoisomer de D-threo de um phenidate na ausência substancial de todos stereoisomers restantes.