A portable laser processing module is adapted to be quickly and easily independently interfaced between a stationary exhaust docking station for fume extraction during in-office use and a portable air processing module for fume extraction during field use. A passageway in the housing connects the work area to an exhaust port which communicates with an inlet port in the docking station or the portable air processing module and ultimately to a blower unit in a facility or in an internal compartment in the portable air processing module which maintains a negative pressure in the work area for removal of fumes, debris, particulates, and contaminants therefrom. Guides are receivable in recesses between the laser processing module and the docking station or portable air processing module for guiding the module thereon, and a gasket seals the exhaust port and inlet port when the module is supported on the docking station or the portable air processing unit. A filtration unit including a filter set may be housed internally of the portable air processing unit.