Magnetic tunnel junction random access memory architecture in which an array of memory cells is arranged in rows and columns and each memory cell includes a magnetic tunnel junction and a control transistor connected in parallel. A control line is connected to the gate of each control transistor in a row of control transistors and a metal programming line extending adjacent to each magnetic tunnel junction is connected to the control line in spaced apart intervals by vias. Further, groups of memory cells in each column are connected in series to form local bit lines which are connected in parallel to global bit lines. The series-parallel configuration is read using a centrally located column to provide a reference signal and data from columns on each side of the reference column is compared to the reference signal or two columns in proximity are differentially compared.