Genetically engineered or transduced hepatocytes which express genetic material of interest introduced or incorporated into them, as well as methods of producing, transplanting and using the genetically engineered hepatocytes. The genetic material of interest can be incorporated through use of a vector, such as a recombinant retrovirus, which contains the genetic material of interest, or by other method.

Projetado genetically ou transduced os hepatocytes que o material genetic expresso do interesse introduziu ou incorporou neles, assim como métodos de produzir, de transplanting e de usar os hepatocytes genetically projetados. O material genetic do interesse pode ser incorporado com o uso de um vetor, tal como um retrovirus recombinant, que contenha o material genetic do interesse, ou pelo outro método.