Compounds having the formula ##STR1## and pharmaceutically acceptable salts and prodrugs thereof are matrix metalloproteinase inhibitors. Also disclosed are matrix metalloproteinase-inhibiting compositions and methods of inhibiting matrix metalloproteinase in a mammal.

Los compuestos que tienen el ## del ## STR1 del fórmula y farmacéutico las sales y los prodrugs aceptables de eso son inhibidores del metalloproteinase de la matriz. También se divulgan composiciones de la matriz y métodos metalloproteinase-que inhiben de inhibir metalloproteinase de la matriz en un mamífero.

 
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