Noel compounds that mimic and/or modulate the activity of wild-type nucleic acids. In general, the compounds are oligonucleotides which contain at least one region of 2'-modified nucleosides connected by alternating phosphodiester and phosphorothioate linkages.

Noel Mittel, die die Tätigkeit der Wildart Nukleinsäuren nachahmen und/oder modulieren. Im allgemeinen sind die Mittel Oligonucleotides, die mindestens eine Region der Nukleoside 2'-modified enthalten, die indem sie phosphodiester und Phosphorothioategestänge angeschlossen werden, wechseln.

 
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