The present invention features formulations, including liquid, semi-solid or solid pharmaceutical formulations, that improve the oral bioavailability of hydrophobic pharmaceutical agents, such as quinazoline-, nitrothiazole-, and indolinone-based compounds. Also featured are formulations for parenteral delivery of such hydrophobic pharmaceutical agents, as well as methods of making and using both types of formulations.

L'invention de présent comporte des formulations, y compris le liquide, semi-finale-solid ou formulations pharmaceutiques pleines, qui améliorent la disponibilité biologique orale des agents pharmaceutiques hydrophobes, tels que la quinazoline -, nitrothiazole -, et les composés indolinone-basés. En outre décrites sont des formulations pour la livraison parentérale de tels agents pharmaceutiques hydrophobes, aussi bien que des méthodes de la fabrication et employer de les deux types des formulations.

 
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